In several vaccine lectures that I have attended in the past four years,
the most current information from our premiere veterinary vaccine researchers,
Dr. Ronald Schultz (Immunologist) and Dr. Richard Ford, (Infectious Disease
Professor, Clinical Director of NC College of Veterinary Medicine), is
that Leptospirosis vaccines are not recommended vaccines.1, 2 Dr. Ron Schultz,
whom lives in a Leptospira endemic area of the country, still does not
recommend the Leptospira vaccines and does not vaccinate his own dogs.3
First let us look at information from the CDC website on the disease
of Leptospirosis as it stands here in the United States. The most current
CDC fact sheet states that Leptospirosis in humans is not a reportable
disease in the United States. The few cases that occur are mostly traced
to Hawaii which is not a part of the continental United States. The disease
does occur more in tropical climates and is reported to have a fatality
rate worldwide in humans of 1-5%. With most of the cases in the US occurring
in Hawaii or in travelers that went to tropical destinations we can put
the exposure of Leptospirosis in the US into proper perspective.4
Indeed while I requested the epidemiological information on Leptospirosis
in the Commonwealth of Massachusetts prior to a lecture promoting Leptospirosis
vaccines in dogs, I found that Massachusetts had never had even one case
of Leptospirosis reported in humans since they started looking for Leptospirosis
.5 There were no cases of Leptospirosis reports in dogs documented and
confirmed for the Commonwealth of Massachusetts.
Again, I gathered this information for the purpose of properly understanding
the true status of the Leptospirosis disease and the need for a preventative
program within the veterinary clinical setting.
Researching the areas of the world that are trouble spots of Leptospira
exposure - Okinawa, Philippines, Sri Lanka, Malaysia, Indonesia, Brazil,
Cuba, Guatemala, Borneo - most of the areas that suffer from this disease
in a natural setting, have a number of common environmental parameters.
One is standing water or flooding, post hurricane flooding and in tropical
areas of increased water fall. US military personnel have seen infections
with Leptospira when at duty in stations in tropical and subtropical locations.
Another factor to consider with Leptospirosis is the presence of rat infestations.
This can be found in slums of Brazil and the crowded areas of rat infested
alleys of the NY Bronx, to the rat infested prisons of Malaysia. Sewer
workers in China are exposed to Leptospirosis; post flood waters from hurricanes
in Cuba bring predictable exposure to Leptospira.
There is also a seasonality of autumn associated with the disease.
People and animals exposed to infected areas of water, ponds and smaller
lakes, hunters and people taking part in water sports are at risk in selected
reservoirs harboring pathogenic serovars of Leptospira. Occupations exposing
the workers to animals - as in butchers and slaughterhouse workers - are
at increased risk, as are veterinarians and farmers. One dairy maid in
the UK lost a pregnancy at 23 weeks due to the first known case of human
intrauterine exposure to Leptospirosis.6 A caution to handling the tissues
of any animals that could become infected with pathogenic strains of Leptospirosis
would be prudent to note; namely in cows, pigs, and dogs. Understanding
the factors that increase the risk of exposure to Leptospirosis is necessary
in understanding how to avoid Leptospirosis exposure.
Last year there was a report of the use of Leptospirosis as a biological
warfare weapon in Somalia, the pathogen being added to the drinking water
supply of soldiers.7 A newly reported reservoir of Leptospira in bats is
also a matter of study .8 California sea lions and harbor seals have been
found to carry Leptospira and Japan has found Leptospira in flying squirrels
imported from the United States as pets from Texas.9,10 Other than
these aforementioned areas, the fact is that the typical veterinary patient
in the continental United States will not be at risk nor exposed
to a pathogenic serovar of this organism that is nevertheless listed
as the most rapidly growing zoonosis in the world.
Last year, the predictable season of post hurricane flooding and Leptospira
exposure in Cuba was handled with the public prescription and use of homeopathy.
This successful use of homeopathy for public health is documented with
over 2.4 million people in Cuba administered two doses of homeoprophylaxis
in 2007 by the Ministry of Health in Cuba. The doses of Leptospira nosode
had been prepared at the Finlay Institute, a center dedicated to development
and production of vaccines. Finlay Institute is a WHO qualified facility
dedicated to research, production and development and produces high quality
homeopathic products in addition to vaccines.11 Understanding that there
are much safer ways to address exposure to Leptospira in the example of
a chemoprophylaxis also is important when the record of adverse events
from Leptospira vaccines are discussed.12,13
..
Outside the United States where recognized pathogenic serovars of Leptospira
exist and certain workers are at higher risk for Leptospira infections,
except for a few weak references of sewer workers and agricultural workers
in Asia, people are simply not vaccinated against Leptospirosis.
The reasons are:
...
#1 the vaccines do not work to prevent infections
#2 the vaccine is associated with adverse events that preclude their
use14
..
So, if exposure to Leptospirosis is so specific, if there are known
adverse events, and if there is a lack of protection from the vaccines
in humans, why are Leptospira vaccines promoted for dogs in the United
States, or in the United Kingdom or in Australia?
..
THE BAD VACCINE
..
There are over 230 serovars of Leptospirosis, only a few which are
pathogenic.15 The vaccines are serovar specific and several factors are
impacted by this information.16 First of all, any vaccine administered
for specific serovars will only create agglutinating antibody to those
specific serovars.17
..
Once vaccinated, the patient’s serum can no longer be a useful record
for diagnostic tests, as the serum antibody titer from the vaccine cannot
be distinguished from antibody caused by natural infection. This
leads to interpretation problems when trying to diagnose the presence of
infection or disease.18
..
Records of multivalent vaccines lead to test results of antibody generation
against serovars that were not even included in the vaccine to begin with.19
This, of course, means that antibodies came from natural exposure, and
not from the vaccine. This leads to problems using the MAT titer
test to even try and determine beyond doubt which serovar was the serovar
of infectivity, if any.20 If the production of antibody following vaccination
were synonymous with immunity (which it is not) or immunization (which
it is not) the obvious conclusion of this information is that vaccination
does not even result in protection.21
..
Due to molecular mimicry with antigens, the unsettling factor for disease
presence is complicated with cross reactivity of the antigens with many
different disease organisms such as Syphilis, Lyme, Legionaries, HIV and
autoimmune disease.22 Put simply, this means that it is difficult to distinguish
between antibodies to this range of diseases. Testing of the patient suspected
with a Leptospirosis disease is now done via the PCR DNA test for the actual
organism retrieved from either blood or urine.
..
Oregon State Veterinary Diagnostic laboratory and IDEXX now both advertise
this PCR testing on the DNA of the actual organism.23, 24 One problem with
the tests is to understand that you should not administer any treatment
prior to obtaining test samples if you want a chance at retrieving useful
information - as even one dose of antibiotics is able to turn a positive
case to negative on the PCR test following treatment.25 Any treatment will
also render a test taken at a later date negative.
..
This would be a good time to let you know how easily Leptospirosis
can be treated. Doxycycline is the antibiotic of choice. This antibiotic
has the ability, even in renal compromise, to sterilize the urinary tract
of Leptospira infection. Doxycycline can be administered to dogs with renal
insufficiency and is effective in both the infection of the blood or urine
stage, clearing the organism from the kidneys.26
..
Since there are so many Leptospirosis serovars out there, and since
the pathogenic strains vary, and since the vaccines cannot guarantee protection
from infection, it would make better sense to not inject your dog with
any Leptospira vaccines.
..
The trade offs to avoiding adverse events from vaccination - not the
least of which can be renal failure within 48 hours of injection, or four
years of dermatitis and puritis - would be the human caretakers actually
knowing their dog is sick with a pathogenic strain and having their dog
presented immediately for treatment.27 To do this, animal guardians need
to be aware of the symptoms of Leptospirosis in the dog.
..
Antibiotic treatment is quickly effective. The possibility of human
infection from their dog disappears after the first day of treatment with
antibiotics, so early detection of a real problem impacts human public
health issues as well.28 Doxycycline (chemoprophylaxis) is also used successfully
to prevent human infections (weekly 200 mg for military personnel without
previous exposure to Leptospirosis who are going for jungle training) when
taken prior to the possibility of Leptospira exposure.29
..
Vaccination with Leptospira is fraught with problems. Leptospira vaccines
cannot even protect the dog from infection with Leptospira or renal colonization.
Leptospira vaccines have little effect on the maintenance and transmission
of the disease in the animal populations in which they are applied.30 The
Leptospira becomes the very source of infection of the humans in contact
with the Leptospirosis vaccinated dog.31 There are several cases that I
am personally aware of that, in the end, I could not say beyond any doubt
that the Leptospira vaccine administered to the dog was not the actual
reason for subclinical infection. Chronic shedding of the Leptospira
in turn infected the humans living in the same household!
Read the paper on the use and overuse of veterinary vaccines leading
to emerging public health issues and realize that use of Leptospira vaccines
in dogs is an obstacle to public health!32
In the case of a duck hunter contracting a case of Leptospirosis, following
the epidemiological field study undertaken by the state of California and
the inability to recover any Leptospira from the bodies of water, the question
needs to be answered if the man became infected through transmission of
the Leptospira from his vaccinated dog.33
There is a cost associated with monitoring the environment to continue
to assess the extent of any purported Leptospirosis serovars causing disease
in a given population. To date there are no such programs set up as the
scarcity of the disease economically makes Leptospira not a “priority”
disease, not one that even needs to be tackled with vaccination. A successful
vaccination program requires that the epidemiological studies are done
to assess the extent of a problem and this is currently not even being
preformed.34
The public and the veterinary doctors usually do not know that this
vaccine does not confer immunity. Challenge studies are rarely done and
the studies I have evaluated are conflicted and ineffective in measuring
immunity in vivo35, 36 Production of Leptospira vaccines are expensive
and labor intensive to the drug companies who must recoup the precious
monies spent to have brought them to market. Is this enough of a
reason to allow the adverse events that follow use of this troubled vaccine?
Most information available to the animal caretakers that come from
self proclaimed “dog experts” on the internet are false. The marketing
misinformation that recommends this vaccine is everywhere. Unfortunately
this includes most of the advice available from veterinary run websites
on the internet, and in the veterinary office in the brochures available
to clients. I found one very fair column on the subject of Leptospirosis
written by a retired veterinarian in Oklahoma, and a great article that
even listed the contraindications for the Leptospira vaccines in dogs by
a veterinarian in Bali - one place that has a serious Leptospirosis problem.37,
38 Why is this? The truth is that veterinarians are painfully inept at
discussing the facts surrounding Leptospirosis because the bulk of their
information comes from the very drug companies that stand to profit or
at least recoup the many monies this troubled vaccine has cost their corporations.
One serious problem veterinarians make is marketing conflict material
for the drug companies. I have seen this misinformation published - not
only in the local newspapers but also on the worldwide web. A Reidsville,
NC veterinary facility that promoted the Leptospira vaccine in partnership
with Pfizer was the source of one particular case.39 The advice of our
professional medical experts is seriously compromised and devalued when
they do not perform due diligence in the release of misinformation marketing
material. The conflict material included a telephone number to the veterinary
facility, so I made a telephone call and heard the veterinary receptionist
continue to disperse marketing misinformation. Where is truth in advertising?
Truth is not even found at the very facilities that administer the jab!
Who then will be held accountable for the adverse events that follow
the administration of Leptospira vaccines? Certainly not the corporations
that make the vaccine, they have no license to censure.
I am including pictures of animals harmed by the Leptospira vaccines
and a listing of those adverse events reported by the clients. Anaphylaxis,
anorexia, fever, dehydration, autoimmune disease, digestive issues, limping,
loud vocalization following vaccination, acute organ failure, renal
failure, liver failure, pancreatitis, death, dermatitis, puritis, cancer,
degeneration of soft tissue - all of these are reports following administration
of the Leptospira vaccine.
Here is another important fact of vaccine use in general……….vaccines
are being linked to death, disease and chronic disability. Vaccines - because
of the immunopathology they activate once the jab has been delivered -
are responsible for the disease that results in those receiving the jab.
Immune reaction to the soup of ingredients delivered in the jab result
in autoantibody production.40 Microbial antigens can also elicit autoantibody
production.41 Indeed vaccines are now found to be responsible for autoantibody
production, autoimmune disease, and cancer! The immunogenetics of autoantibody
and autoimmune diseases are under genetic control; however the inciting
disturbance to elicit gene response is from the jab itself.42 Vaccines
lead to mutations of the genome, autoimmune disease in one generation leads
to genetic disease in the next. Vaccines generate genetic impact that not
only determines the severity of the immune response in natural
infections but also dictates response from tissue histocompatibility markers
and the expression of autoimmune disease with repeated exposure to antigens
with subsequent vaccine administrations. The histocompatibility markers
on the tissues are also reactive to the results of the jab. The genetic
compromise that occurs to anyone’s genome receiving the jab has never been
researched by the drug manufacturer’s that produce vaccines and therefore
prove that vaccine safety and efficacy have never been determined by the
government regulatory agencies that license and unleash these products
upon the populations.
I
ndeed,
research is now available to show how the histocompatibility sites of human
and animal tissues are reacting with vaccine-injected antigens that in
turn are responsible for the adverse, lethal disease pathology that kills
or dis eases the patient.43 Indeed there are examples of the very vaccine
antigen to immune cell response with both Leptospira and Lyme disease vaccines
producing the same pathology as the natural infection itself.44, 45, 46
To clarify, these vaccines can cause the disease pathology that we
are vaccinating against. In some cases with viral vaccines they can even
result in the viral disease itself.
This brings more understanding to the statement in the book ‘Vaccination
Examining the Record’ by Judith A. DeCava: “a person not vaccinated has
ONE RISK, catching the disease, where a vaccinated person has TWO RISKS;
catching the disease and damage from the vaccine”.47 We now know that the
vaccines have not been safety tested and they have not really been proven
effective in providing true immunity.
The immune system
reactivity vaccines are responsible for can be the expression of the adverse
events and diseases that follow vaccine administration.48 Specific
Leptospirosis severity may be associated with the intensity of the humoral
immune response. Vaccines and previous natural exposure would determine
this humoral immune response.49 Therefore the “gene environment”
which is impacted by every jab delivered can determine the T cell activation
and immune complexes, auto antibodies and cytokine cascade that results
not only with future natural exposure to antigen but with every additional
jab delivered. The making of a “super antigen” and lethal consequences
would at the hands of the vaccine administrators.50 This is why Dr. Ron
Schultz is on record with a minimal vaccine protocol and has said you better
have a good reason for injecting because any time you inject you could
kill the patient.
The hypothesis is that the disease of Leptospirosis is in actuality
immune mediated. I believe I have support of this in the reporting
by doctors of the use of pulsed steroid treatment to save the kidney in
cases where the symptoms are the very description of immune mediated dis
ease itself. Patients that were treated with pulsed steroids were too far
from immediate medical facilities and were treated in the field situations
with high doses of pulsed steroid. Immunosuppressive dosing of steroids
was able to save them from renal failure and the immune mediated pathology
of the disease until they were able to reach critical care facilities and
fluid support for the kidneys.51 This means the antigens in the vaccine
are just as capable of producing disease as in the natural infection because
of the interaction of the antigen and the immune cells, is the dis ease!
Another factor now understood is that in direct opposition to the germ
theory of Pasteur, it appears this is another example of the proof that
Microbiologist Antoine Bechamp was correct about disease and the theory
of “terrain”. Terrain theory states that it is the individual’s system
that determines dis ease and the individual response to presentation of
the antigen to the patient’s immune cells. However, multiple administrations
of vaccines hyper sensitize the patient to a real crisis, and when antigen
and immune cells collide, dis ease results.
So beware the medical professionals that are not Leptospirosis literate
and are just promoting corporate marketing information. Misinformation
seems to me to be the majority of Leptospirosis information available.
Marketers - especially now in this tight economy - are engaging all of
their “business resources” in order to generate revenue. Adverse event
associated vaccine administration are a real boon to the coffers when the
adverse events follow the cost of vaccinations.
Pfizer sponsored”scientific” papers on Leptospira are sponsored with
“educational “grants in order to produce recommendations for vaccination
of the dog without proof that the vaccine is safe or effective. They use
words like “likely” and “appears’ to expotentialize the nonexistent benefit
of vaccination. They are “reaching” in their efforts to provide a benefit
for vaccine use. They say these vaccines “appear” to be effective. They
write off any adverse events from the vaccines stating “published data
to validate these concerns are lacking because there is no independent
mechanism to report vaccine reactions in the US”.52
The drug companies and the veterinarians that are paid as corporate
mouthpieces can all hide behind this statement and all help keep independent
mechanisms for reporting adverse vaccine events from manifesting by influencing
government. The repeatable phenomena that continue to follow vaccinations
are not merely “coincidences”.
A Pfizer mouthpiece states that “they would advise to strongly consider
vaccination” because “they appear to work”, yearly boosters “appear to
be necessary”. They admit that the weak spot is “vaccine development” and
“diagnostic assays”, that reemergence of this disease could very well be
the result of vaccine programs! 53
When I pressed for the proof from Merial that their Leptospira vaccines
did indeed provide an entire year of “immunity” they finally sent me an
article that did not even test their vaccines. The company forwarded work
from Intervet in the Netherlands. Intervet is the source of much conflict
in the UK for mounting yearly marketing campaigns in order to advocate
yearly vaccinations of pets, despite the fact this is not a recommendation
from the World Small Animal Veterinary Association or our AVMA or AAHA,
or in Australia. The paper that was supposed to prove the worthiness of
the Leptospira vaccines was conflict material that also failed to properly
test vaccinates in a method that would prove immunity.
The paper was also not even using the Merial vaccines in their study.
The conflict work was performed at the Dept. of Bacteriological R &
D for Intervet International BV in the Netherlands.54
If you read the paper A Shot in the Dark about the scandal surrounding
the push to vaccinate dogs in the UK with Leptospirosis vaccines, despite
the lack of proof of the existence of a Leptospirosis problem. You
will find out that the drug companies conspired to format a market for
their product with only anecdotal evidence of the existence of any Leptospirosis
problems.55 What truthful
information or facts do we really have to base due diligence on?
This problem of the drug company making a market for their product
when a risk for the disease does not exist, or when there is a risk of
vaccine induced adverse events, is not beneficial to the animals is counter-productive
for animal welfare. A few examples of this happening in human medicine
with Glaxo Smith Kline and the Hep B vaccine, the Merck Gardasil vaccine
and the Bird Flu and Swine flu vaccines have all resulted in a call for
investigations and criminal charges to be brought against the WHO.56, 57
The WHO Vaccine Advisor, Juhane Eskola made over 6 million Euros researching
vaccines he then advised the WHO to recommend for the recent swine flu
“pandemic”. Similarly, the CDC Childhood Vaccine Advisor, Dr. Paul Offit
made so much money with Merck making a rotavirus vaccine that he said “it
was like winning the lottery”. Now Professor Ulrich Keil Director of WHO
Collaborative Center for Epidemiology is admitting to PACE investigation
that the vaccine advisors are often employees of the pharmaceutical companies
and the WHO is only a screen for unearned commercial promotion of pharmaceutical
products.
Indeed, even the US courts hearing the case of Lymerix vaccine damage
and ordering the recall of the adverse event associated vaccine stated
that the federal employees should never be allowed to consult in areas
where they set federal policy. In veterinary medicine, many researchers
are indeed employees of the pharmaceutical companies they become the mouthpiece
for. Despite being on faculties of our leading veterinary institutions,
many have their research grants supplied to them from the pharmaceutical
industry.
Vaccine adverse events will remain anecdotal so long as government
and industry continue to protect vaccine use. When the only safety or effectiveness
studies come from conflict sources - those that stand to profit from the
sale and use of the vaccines - we need to understand that corporate integrity
or lack thereof is the only unit of measure.
This year another effort by Canine Health Concern in the UK is once
again trying to stop the unethical marketing of vaccine protocols that
are not within the standard of care for veterinary medicine and constitute
fraud. This letter of concern has been signed by many veterinary professionals
in the hopes that unsafe and dangerous vaccines are not promoted to the
public from drug marketers.58
The Leptospira vaccines are not safe. Pfizer gives ‘immunization
support guarantees” and this says, ‘buy ours, it is the best”. As they
talk about “serovar shifts” and discuss that “diagnostic assays are
wrought with problems”; that they cannot explain how high MAT titers
are obtained against serovars not even in the vaccines, that the vaccine
itself can produce disease in the dog, you see quickly over a dozen ways
to beat the ‘immunization guarantee”.59
Cornell helped Pfizer with the “educational” paper and now, we see
Cornell has a” better vaccine” as they have yet another idea how to make
an effective Leptospira vaccine. Cornell disses the aluminum adjuvant used
for a century in veterinary vaccines. The aluminum adjuvant; which
has been in all the Leptospira vaccines even now to this very day, despite
being found to cause cancer. Cornell is now reporting that the aluminum
adjuvant used for five decades is now known to be “unreliable”. They
say it “destroys the antigens structure” and that it” degrades amino acid
sequence “.60 Did the aluminum do this to the genomes of the victims receiving
these adjuvants? Apparently so as the WHO in 1999 declared these adjuvants,
the same found in children’s vaccines, as “carcinogenic” in the IARC.61
Cornell wants to take a whack at putting yet another Leptospira
vaccine out there. Cornell’s Baker Institute of Animal Vaccines will make
yet another type of vaccine and this one will be better, this one
is made with genetically engineered bacteria genes from E. coli, this one
will be safe, try this one.62 (January 25, 2010)
Understand that there is no backbone for support of vaccination. The
most widely used statement from disease illiterate professionals marketing
the vaccines is: “the long history of well established success that vaccines
have been responsible for the control of infectious disease” is as long
as the history of vaccine use and as much a figment of the promoter’s imagination
as I have ever seen consistently appear as defense for vaccinologists.
There is no proof that vaccines create immunity. Vaccines are linked to
the generations of immune reaction diseases that now plague highly vaccinated
populations. As my colleague Dr. Stephen Blake has said over and
over,” never before in the history of man has there ever been a greater
medical assumption more responsible for the death and disease than the
use of vaccines as we know them today”.
Know the risks for natural infection, seek immediate treatment if your
dog gets sick, and realize the germ is not the problem; the individual’s
immune system is the determinant. Optimal nutrition is the key to
immune health .Prior genetic damage from vaccines should be considered.
Become proactive in the search for truth, never assume the medical professional
performs due diligence. Poison is poison no matter if injections contain
toxins, chemicals, heavy metals, viruses and microbial protein, antibiotics
and fungi stats or genetically engineered monsters.
Supporting
Your Animal's Immune System Naturally
Having the “new thing” with genetically engineered products will not
be proven any safer than the earlier poisons. Know the promoters will not
perform due diligence in establishing safety, that our government to date
accepts safety studies from this conflict source and provides for no independent
testing, that the vaccine-promoting professionals, the doctors, will not
be expected to perform due diligence in the researching of these products
and at this time still do not recognize the vaccine induced disease and
adverse events nor report them to any independent monitoring system. Understand
that they will unleash this vaccine without really knowing if the vaccine
is safe or effective, just as they have for all the vaccines that have
come before.
Intervet Schering Plough is revving up for their annual vaccine propaganda
marketing in the UK again, promoting unsafe vaccines on the anecdotal evidence
that there is even a need for the vaccine in the first place.63 The only
protection from this marketing mania is to know the lack of science behind
both the making and administration of these vaccines. Understand that the
client will not have recourse against these marketing giants when their
pets become ill. Understand that drug companies are responsible and yet
are unable to be held accountable. To the vaccinologists out there, Dr.
Ron Schultz says it is an indefensible practice. Culpable responsibility
does lie in the hands of the administrator of the jab. Only the informed
animal owner will understand this so pass the information forward!
The
horrific results of allowing the unecessary vaccination of companion animals
to continue
Leptospira is a “killed”
vaccine and is associated with clinically significant adverse reactions.
According to the 2003 AAHA Guidelines (Page 16), "...killed vaccines are
much more likely to cause hypersensitivity reactions (e.g., immune-mediated
disease)." Further, the AAHA task force reports on Page 18 that,
"Bacterial vaccines, especially killed whole organism products …..are much
more likely to cause adverse reactions than subunit or live bacterial vaccines
or MLV vaccines, especially if given topically. Several killed bacterial
products are used as immunomodulators/adjuvants. Thus, their presence in
a combination vaccine product may enhance or suppress the immune response
or may cause an undesired response (e.g., IgE hypersensitivity or a class
of antibody that is not protective)."Kris
L. Christine - more...
Other articles by Dr. Jordan
Cancer
in our pet population, why is it on the rise?
Lyme
disease and Lyme Vaccine Disease
How
vaccines dysregulate the immune system and impact genetic control over
disease expression
5th Annual
Joint American Homeopathic Conference - Poster Session 2010
References
1. Schultz R, Everything
You Need To Know About Vaccines. Seminar Danbury, CT, June 15, 2007.Sponsored
by Cavaliers of the Northeast.
2. Ford R DVM MS Diplomate
ACVIM, Vaccines and Vaccination Building the Protocol-Implementing the
Guidelines. Framingham, MA July 25, 2007.Sponsored by Merial.
3. Schultz R, Everything
You Need To Know About Vaccines. Seminar Danbury, CT. June 15, 2007.Sponsored
by Cavaliers of the Northeast.
4. CDC Leptospirosis Information
Sheet Http://www.cdc.gov/ncidod/dbmd/diseaseinfo/Leptospirosis
5. Hershey-Grove D MPH,
Commonwealth of Massachusetts, executive Office of the Health and Human
Resources, Department of Public Health, bureau of Communicable Disease
Control, Office of Integrated Surveillance and Informatics, William A.
Hinton State Laboratory Institution,305 South Street, Jamaica Plain, MA
02130.
6. Aker N, James ED, Johnston
AM et al, Leptospirosis in pregnancy: an unusual and relatively unrecognized
cause of intrauterine death in man. Journal of Obstetrics and Gynecology
1996 May, 16; (3):163-165.
7. Kasasira R and Bagala
A, UPDF soldiers poisoned in Somalia. Kampala http://www.monitor.co.ug/artman/publish/news/UPDF_soldiers_poisoned_in_Somalia_88893.shtml.
8. Vashi NA, Reddy P, Wayne
DB, Sabin B, Bat-associated Leptospirosis. J Gen Intern Med. PMID:
200112224 PubMed [Epub ahead of print].
9. Stock D, Children’s Pool,
LaJolla, California Nov 8, 2009:1-2
10. Masuzawa T, Leptospirosis
in squirrels imported from the United States to Japan. US National Center
for Infectious Diseases 2006.
11. Campa C, Varela LE,
Gilling E et al., Homeoprophylaxis Homeopathic Immunization and Nosodes
against epidemics: Cuban experience in Nosodes 2008 International Meeting
Proceedings Havana, Cuba 10-12 Dec 2008.http://www.finlay.sld.cu/nosodes/en/ProgramaNosodes2008.pdf
12. McClain JBL, Ballon
WR, Harrison SM, Doxycycline therapy for Leptospirosis. Ann Intern Med
1984 100:696-698.
13. Takafuji ET, Kirkpatrick
JW, Miller RN et al., An efficacy trial of Doxycycline chemoprophylaxis
against Leptospirosis. NEJM. Feb 23 1984; 310 (8):497-500.
14. Levett PN and Haake
D, Leptospira: Species (Leptospirosis) Elsevier http://www.elsevierjapan.com
page 5.
15. Smythe LD, Smith IL,
Smith GA et al., A quantifiable PCR (Taqma) assay for pathogenic Leptospira
spp. 2 BMC Infect Dis 2002 July 8;2(1):13.
16. Koizumi N, Watanabe
H, Leptospirosis vaccines: Past, Present and Future. J Postgrad Med 2005;
51:210-4 (page 210).
17. Goldstein RE, Leptospirosis
Epidemiology Pathogenesis and Zoonotic Impact on Veterinary Practitioner.
Insights in Veterinary Medicine 2007 Aug; 5(2):3.
18. Goldstein RE, Leptospirosis
Epidemiology Pathogenesis and Zoonotic Impact on Veterinary Practitioner
Insights in Veterinary Medicine 2007 Aug; 5(2):5.
19. Goldstein RE, Lin RC,
Lanstron CE et al., Influences of infecting serogroup on clinical features
of Leptospirosis in dogs. J Vet Intern Med.2006: 20(3):489-494
20. Levett PN, Usefulness
of serologic analysis as a predictor of the infecting serovar in patients
with severe Leptospirosis. Clin Infect Disease 2003:36; 447-452.
21. Schultz R, Everything
You Need To know About Vaccines .Danbury, CT, June 15, 2007. Sponsored
by Cavaliers of the Northeast.
22. Bajani MD, Asford DA,
Bragg SI, et al., Evaluation of four commercially available rapid screening
tests for diagnosis of Leptospirosis. J Clin Microb. 2003; 41:803-809.
23. Oregon State University
of Veterinary Diagnostic Laboratory Leptospirosis Real Time PCR DNA for
acute onset of illness http://oregonstate.edu/vetmed/vdl/vdl.htm
24. IDEXX Introduces Real
PCR TCM Test for canine Leptospirosis http://www.idexx.com/pcr
25. Goldstein R, Canine
Leptospirosis. Department of Clinical Sciences, College of Veterinary Medicine
Cornell University, Ithaca, New York. Email rg225@cornell.edu
26. Goldstein RE Leptospirosis
Epidemiology and Pathogenesis and Zoonotic Impact on Veterinary Practitioners.
Insights in Veterinary Medicine Aug 2007:5 (2):4.
27. Schultz R, What Every
Veterinarian Needs to Know About Canine and Feline Vaccines and Vaccination
Programs with an emphasis on recombinant Vaccines, Warwick, RI April 16,
2008 Sponsored by Merial.
28. Goldstein R, Canine
Leptospirosis epidemiology and Pathogenesis and Zoonotic Impact on Veterinary
Practitioners. Insights in Veterinary Medicine Aug 2007:5(2):4.
29. Takafuji ET, Kirkpatrick
JW, Miller RN et al., An efficacy trial of Doxycycline chemoprophylaxis
against Leptospirosis NEJM Feb 23 1984:310(8):497-500.
30. Levett PN Leptospirosis.
Clin Microbial Rev 2001; 14:296-326.
31. Feigin RD, Lobes LA,
Anderson DM, et al., Human Leptospirosis from vaccinated dogs. Am Intern
Med 1973:79:777-785.
32. Berkelman RN, Human
Illness Associated with the use of veterinary vaccines. Emerging Infections
CID 2003 (1 August); 37:407-414.
33. Meites E, Jay MT, Deresinski
S, et al., Reemerging Leptospirosis, California. Emerging Infectious Diseases
March 2004; 10(3):406-411. http://www.cdc.gov/eid
34. Srivastava SK, Prospects
of developing Leptospira vaccines for animal. Indian Journal of Medical
Microbiology. 2006; 24(4):331-336.
35. Klassen HL, Molkenboer
MJ, Vrijenhoek MP, Kaashoek MJ, Duration of immunity in dogs vaccinated
against Leptospirosis with a bivalent inactivated vaccine. Vet Microbiol
2003 Aug 29; 95 (1-2):121-132.
36. Wohl JS, Canine Leptospirosis
in the Compendium Nov 1996; 18 (11):1215-41.
37. Fauks WF, Dog owner
worries about Leptospirosis vaccine reaction. The Edmond Sun http://www.edmondsun.com/features/local_story_285200506.html
38. Bali Dogs, Leptospirosis
no longer recommended for household urban dogs http://kertabesung.blogspot.com/2009/02/leptospirosis-in-dogs.html#links
39. Reidsville Veterinary
Hospital partnering with Pfizer http://www2.godanriver.com/gdr/news/local/rockingham_news/article/leptospirosis
40. HogenEsch H, Azcona-Olievera
J, Scott-Moncreiff C, et al., Vaccine-induced Autoimmunity in the Dog.
Adv Vet med 1999; 41:733-744.
41. Kuo P, Kowal C,
Tadmor B, et al., Microbial Antigens can elicit autoantibody production
a potential pathway to autoimmune disease in Annals of the NY Academy of
Science 1997;815 (B):230-236.
42. Olsen NJ, Chen PP, Immunogenetics
of auto antibodies and autoimmune disease. Current Opinion in Rheumatology
1991 Jun; 3(3):391-7.
43. Oldstone MBA, Relationship
between major histocompatibility antigens and disease. Bull World Health
Organ, 1975; 52:479-486.
44. Latov N, Wu A, Chin
R et al., Neuropathy and cognitive impairment following vaccination with
the Osp A protein of Borrelia burgdorferi. Journal Peripheral Nerve Society,
Inc., 2004; 9 (3):165-167.
45. Otto A, Lyme Vaccine
Linked to Autoimmune Arthritis. Pharmacy Today January 2001;7(1):10
46. Rathinam SR. Ocular
Leptospirosis. Curr Opin Opthalmol 2002; 13:381-6.
47. DeCava J, Vaccination
Examining the Record. Selene River Press, Fort Collins, CO 2005 page 30.
48. Moore GE, Guptill LF,
Ward MD et al., Adverse events within 72 hours of vaccination. JAVMA 2005
Oct 1; 227 (7):1102-8.
49. AO batulkachi RC, Daher
EF, Camargo ED et al., Leptospirosis severity may be associated with intensity
of humoral immune response. Rev Int Med Trop Sao Paulo 2002; 44:79-83.
50. WHO Memoranda Virus
associated immunopathology; animal models and implications for human disease2.
Cell mediated immunity autoimmune disease genetics and implications for
clinical research. 1972;47 (2)
51. Person DA, Leptospirosis
in the Pacific; Tripler Army Medical Center. Medical Surveillance Monthly
Report; 4:12-14.
52. Goldstein R, Canine
Leptospirosis epidemiology and Pathogenesis and Zoonotic Impact on Veterinary
Practitioners. Insights in Veterinary Medicine Aug 2007:5(2):4.
53. Goldstein R, Canine
Leptospirosis epidemiology and Pathogenesis and Zoonotic Impact on Veterinary
Practitioners. Insights in Veterinary Medicine Aug 2007:5(2):4.
54. Klassen HL, Molkenboer
MJ, Vrijenhoek MP, Kaashoek MJ, Duration of immunity in dogs vaccinated
against Leptospirosis with a bivalent inactivated vaccine. Vet Microbiol
2003 Aug 29; 95 (1-2):121-132.
55. Cohen Hsiu-Yi, A Shot
in the Dark. Dogs Today Nov 2008:15-19 www.dosgtodaymagazine.co.uk
56. Girard M, WHO recommendations
scientific flaws or criminal misconduct. Journal of American Physicians
and Surgeons 2005; 11:22-23.
57. Wodarg W, Faked pandemics,
a threat to health. PACE Plenary session social affairs Council of Europe
to investigate WHO Jan 25-29, 2010.
58. O’Driscoll C, Complaint
letter against Intervet Ltd’s National Vaccination Month to Advertising
Standards Authority in London, UK. 4 Mar 2008.
59. Fort Dodge Dear Doctor
News updates and practice tips for today’s veterinarians Oct/Nov. 2004;
1(3).
60. WHO IARC International
Agency for Research on Cancer; Summaries and evaluations surgical implants
and other foreign bodies 1999 Feb 23; 74:24305-310.
61. Ramanujan K, Study;
new vaccine delivery system may be more effective .Provided by Cornell
University http://www.physorg.com/news183663284.html
62. Intervet Ltd-National
Vaccination Month Campaign
Patricia
Jordan, DVM Graduated from North Carolina State University in l982 Magna
Cum Laude B.S. Microbiology Completed Honors Program in Medical Microbiology.
Graduated from the University of North Carolina at Wilmington with a B.S.
in Medical Technology Dean's List Premed Graduated from the North Carolina
College of Veterinary Medicine with a Doctorate in Veterinary Medicine
Externship at the University of Berne, Berne Switzerland Large Animal Medicine
and Surgery Externship at the New Bolton Center University of Pennsylvania
Equine Medicine and Surgery Research Scientist for the NIEHS (National
Institute of Environmental and health Sciences) under Dr. John McGlaughlin
in Toxicology Nominated for the 1986 Pubic Health Epidemiology Award for
the NC College of Veterinary Medicine Certified in Veterinary Acupuncture,
Traditional Chinese Veterinary Medicine & Herbology, Tui Na and
a student of the Chi Institute in Reddick, Florida under Dr. Huisheng Xie
and South China University of Agriculture, currently finishing the Master's
Program in Traditional Chinese Veterinary Medicine. Dr. Patricia Jordan
has been a member of the AVMA (American 
Veterinary
Medical Association) for the past 25 years and a practicing veterinarian
for the past 23 years. Establishing four different veterinary facilities,
originating six new veterinary facilities, certified by the North Carolina
Veterinary Medical Board. Dr. Jordan has been on the front line of examining
the effects of the veterinary vaccine protocols in the United States; she
has been licensed in over a dozen states and has visited practices in over
13 states to observe first hand the effects of the current vaccine protocols.
Dr. Jordan is the author
of Mark
of the Beast: Hidden in Plain Sight - This book is essential
reading for pet owners, animal lovers and everyone seeking to know the
truth about vaccine issues. The book title, Mark of the Beast, sums up
the author's views on the medical practise of vaccination. Dr Patricia
Jordan is a highly qualified veterinary surgeon with more than 24 years
experience. Her observations and conclusions are based upon scientific
evidence as opposed to the propaganda and junk science disseminated by
pharmaceutical companies in their ever increasing need to maximize profits.
Dr Jordan cites research studies showing that annual vaccinations are totally
unnecessary and especially in respect of rabies where over vaccination
is causing genetic changes and violent behaviour in animals including horses.
This annual regime financially benefits veterinary business practices and
pharmaceutical companies at the expense of pet owners and their suffering,
short lived companions.
Articles by Dr. Jordan
Cancer
in our pet population, why is it on the rise?
Lyme
disease and Lyme Vaccine Disease
How
vaccines dysregulate the immune system and impact genetic control over
disease expression
5th Annual
Joint American Homeopathic Conference - Poster Session 2010
There
is a problem with Leptospirosis Vaccines
"Adverse events diagnosed
within three days of vaccine administration in dogs 4,678 adverse events
(38.2/10,000 dogs vaccinated) were associated with administration of 3,439,576
doses of vaccine to 1,226,159 dogs. The VAAE rate decreased significantly
as body weight increased. Risk was 27% to 38% greater for neutered versus
sexually intact dogs and 35% to 64% greater for dogs approximately 1 to
3 years old versus 2 to 9 months old. The risk of a VAAE significantly
increased as the number of vaccine doses administered per office visit
increased; each additional vaccine significantly increased risk of an adverse
event by 27% in dogs." Journal
of the American Veterinary Medical Association
5th Annual Joint American Homeopathic Conference
- Poster Session 2010
How vaccines dysregulate the immune system and impact genetic control
over disease expression Presented by
Dr. Patricia Jordan
Classification of Immune Responses Body defense mechanisms Innate and
adaptive immunity.
Cell
mediated responses (Th1)
Lymphocytes, (CD1, CD 2, CD3, CD4, CD8) monocytes- macrophages and
natural killer (NK) cells (principal components) Cytokines
Humoral responses (Th2) involve soluble components including immunoglobulins
(antibodies) [Igs-IgG, IgM, IgA, IgE, IgD], class switching, antibody gamma
globulins and complement proteins
Immune System Components Genetic
Major histocompatibility complex (MHC) system Chromosome, gene, haplotype,
and polymorphism and super gene family molecules.9 MHC genes and include
[HLA-A, HLA-B, HLA-C, HLA-DPA 1, HLADPB1, HLA-DQA1, HLA-DQB1, HLA-DRA and
HLA-DRBI.] MHC region divided into three regions Class I (HLA-A, B and
C) Class II (HLA-DP, DQ and DR) and Class III genes encode complement components
(C2, C4 and Factor B), cytokines (TNF-?) MHC genes display high levels
of allelic diversity
Activation of Adaptive Immunity Innate immunity may trigger adaptive
immune
responses thru Antigen processing and presentation by macrophages and
dendritic cells .The evolution of the immune system is a direct consequence
of pathogen-exerted selection pressure. It is particularly those qualities
like progressive development of humoral and cellular adoptive immunity,
Major Histocompatibility Complex (MHC), variable class I and class II genes,
precise mechanisms of immune recognition and long-term immune memory that
reflect the fundamental evolutionary advancement of the vertebrate immune
system. In evolution the survival advantage imposed by an extremely reactive
immune system is jeopardized if that system turns against the host and
causes "self" destruction. Vaccination is an abnormal pathogen presented
in an abnormal route (injection) and influences the entire immune system
in an unnatural way, leading to unnatural evolutionary selection where
the results are dys regulation of the immune system, disruption of TH1
bias, atrophy of mucosal, increased inflammation, loss of specification
and control. Vaccination dysregulates the immune system and genetically
impacts the HLA (MHC) leading to an abnormal expression of disease susceptibility.
The vaccine is no more a reflection of the actual environmental challenges
faced by those vaccinated than the now dysregulated immune system is a
reflection of intelligent design or natural selection. Vaccines are genotoxic;
corrupted genomes are leading to the loss of the organic self. Vaccines
are responsible for autoimmune, cancer, Type I-IV reactions, allergies,
asthma, atopy anaphylaxis, eczema, organ failure, neurological, behavioral
disease and death.[List is not complete] Vaccine disease is the root of
our dys regulated immune system and the dys regulated immune response.
Anything that alters DNA coding is able to affect genetic expression of
disease
Charles W. Brown, DVM
- "My colleagues and I have found this product to be very effective in
modulating the immune system. Transfer factor is a
"soup" of immune-modulating factors, which contains a leukocyte-type molecule
that can passively transfer immunity from one mammal to another by stimulating
cell-mediated immunity and is antigen specific.
Scientifically
Studied: 4Life
Transfer Factor Plus Tri-Factor Formula was developed by 4Life
researchers and scientists in an effort to maximize immune system support.
Results of an independent study conducted at the Russian Academy of Medical
Science conclusively showed that 4Life Transfer Factor Plus Tri-Factor
Formula propelled Natural Killer (NK) cell activity to a remarkable 437
percent above normal immune system response. No matter what the immune
system needs, 4Life Transfer Factor Plus Tri-Factor Formula delivers powerful
support to help you achieve a strong and healthy immune system that knows
exactly what to do, when to do it, and how to get it done quickly. It combines
the intelligence of 4Life Transfer Factor E-XF, the intuition of NanoFactor,
and the power of 4Life’s proprietary Cordyvant blend to regulate, boost,
and balance your immune system. Scientific studies report that this Plus
Formula can boost immune cell responsiveness 437
percent above normal immune system response.
Shirley's testimonial
- April 20002
When my 11 year old dog,
Shasta, suffered a series of illnesses and a stroke which left her
paralyzed in the hind legs, I treated her with homeopathy
and herbal extracts and she recovered within a
few hours. However, her vitality was very low. I din't think she was going
to make it through the Spring. After a couple of weeks on the Transfer
Factor Plus (human formula) and homeopathy and herbal extract and rest
her energy level and vitaliy improved remarkably. She appears to be back
the way she was 2 years ago: frisky and playful.
Shirley
more
on my dogs' recovery with homeopathy).
Veterinarians recommend
the human formula, Transfer Factor Plus instead of
the pet formula for their sick animals. I find it is easier to give the
content of a small capsule of high potency of TF Plus, to very sick dog
or cat, especially if they have difficulty eating. The Canine and Feline
Complete formulas contain yeast and some dogs have a sensitivity to yeast
which may give them the run. Since Shasta is is sensitive to yeast I give
her the Transfer Factor Plus (human formula) which I think is a more potent
immune booster. I started by giving her one capsule of TF plus (I shoved
a capsule in her mouth or mixed it in her food) for 3 consecutive days.
As she did well on one capsule, I increased the dosage to 2 capusles a
day (one morning and one evening). A few weeks later, as she was doing
much better, I decreased the dosage to one capsule a day as a maintenance
dosage. . Shirley
Customary disclaimer: Please check with your veterinarian
prior to giving your pet dietary supplements that are intended for human
consumption.
More information
about Transfer Factor: articles by doctors and veterinarians
Information
where to purchase Transfer Factor
Do
you have a question about holistic animal health or need assistance? contact
Shirley or call 323-522-4521 or 323-389-0560
Most
Popular Life-Giving Supplements for Animals
Dr.
Jones DVM - "The Truth Behind The Pet Food Recall"
Natural
Health for Women:
